In this talk we will illustrate a project whose aim is to exploit formal models and languages used in software formal verification, for the design of innovative systems to be applied in Biology. We will briefly describe the Simpathica (Simulation of Pathways and Integrated Concurrent Analysis) tool, integrating mathematical and logical approaches to the study of biochemical networks. We will conclude addressing algorithmic and expressivity issues and problems related with the use of standard/hybrid automata, model checking and logical languages in the context of Systems Biology