We consider the framework of functions of Bounded Variation for some Imaging problems (mainly denoising and inpainting), highlighting the main properties of Total Variation (TV) regularisation. The main challenges when considering these models are on one hand the tradeoff between the quality of the reconstruction and the computational costs that, for higher regularisation models, are generally quite high and, on the other hand, the optimal setup of the experiments in order to get accurate results. We tackle the former issue by considering a numerical strategy that breaks down the numerical methods solving the higher-order PDEs involved into easier parts acting typically in one direction only (ADI splitting schemes). The central part of the seminar will address the latter issue, i.e. the selection of optimal parameters for a general TV-denoising model. We formulate the problem by means of a bilevel optimisation approach where the noise of the image is learned by means of a dictionary of images. This approach is normally used in medical imaging applications (for example, MRI and PET) and allows a robust and accurate estimation. Due both to the large size of the dictionary considered and to the nonsmooth nature of the constraints, the brute-force numerical solution of the model is computationally demanding. We consider dynamic sampling schemes combined with a BFGS optimisation method to solve the problem in an efficient and accurate way. The final part of my talk will deal with the the case of spatial dependent parameters, i.e. when the TV regularisation adapts to the underlying image structure for the case of localised noise by the introduction of a nonsmooth L^1-term enforcing sparsity in the cost functional. This is a joint work with Dr. Carola-Bibiane Schšnlieb, University of Cambridge (UK) and Dr. Juan Carlos De Los Reyes, ModeMat, Quito (Ecuador).